1-Piperazinecarboxylic acid, 4-[(2-aminophenyl)methyl]-, 1,1-dimethylethyl ester
tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate
CAS: 885278-02-4
Molecular Formula: C16H25N3O2
1-Piperazinecarboxylic acid, 4-[(2-aminophenyl)methyl]-, 1,1-dimethylethyl ester - Names and Identifiers
| Name | tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate |
| Synonyms | LogP 2-(4-Boc-piperazin-1-yl-methyl)aniline 2-(1-Boc-piperazin-4-yl-methyl)-aniline tert-Butyl 4-(2-aminobenzyl)piperazine-1-carboxylate tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate 1-Piperazinecarboxylic acid, 4-[(2-aminophenyl)methyl]-, 1,1-dimethylethyl ester |
| CAS | 885278-02-4 |
| InChI | InChI=1/C16H25N3O2/c1-16(2,3)21-15(20)19-10-8-18(9-11-19)12-13-6-4-5-7-14(13)17/h4-7H,8-12,17H2,1-3H3 |
1-Piperazinecarboxylic acid, 4-[(2-aminophenyl)methyl]-, 1,1-dimethylethyl ester - Physico-chemical Properties
| Molecular Formula | C16H25N3O2 |
| Molar Mass | 291.39 |
| Density | 1.137g/cm3 |
| Boling Point | 413.802°C at 760 mmHg |
| Flash Point | 204.061°C |
| Vapor Presure | 0mmHg at 25°C |
| Refractive Index | 1.567 |
1-Piperazinecarboxylic acid, 4-[(2-aminophenyl)methyl]-, 1,1-dimethylethyl ester - Introduction
tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate is an organic compound whose chemical formula is C16H25N3O2. The following is an introduction to some of its properties, uses, formulation and safety information:
Nature:
-Appearance: tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate is a white crystalline solid.
-Solubility: It is poorly soluble in water, but soluble in organic solvents such as ethanol and dichloromethane.
Use:
-Drug research: tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate is commonly used in drug research, especially for the synthesis of biologically active compounds.
-Target compound synthesis: It can also be used to synthesize target compounds with specific functions.
Preparation Method:
The preparation method of tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate can be carried out by the following steps:
1.4-piperazinone reacts with benzylamine to generate 4-(2-benzyl) piperazine -1-one.
2. Reaction of 4-(2-benzyl) piperazin -1-one with tert-butyldimethylsilamide to generate the corresponding silicone.
3. react with tert-butyl formate to generate tert-butyl 4-(2-benzyl) piperazine -1-carboxylate.
4. Finally, tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate is generated by reaction with ammonium butyrate.
Safety Information:
- tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate has limited safety and toxicity information, so it needs to be handled with caution. -Appropriate personal protection measures should be taken during use, such as wearing gloves, goggles and laboratory coatings.
-In case of contact, rinse immediately with plenty of water and seek medical help.
- tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate should be stored in a dry, cool place, away from ignition and strong oxidants.
The above information is for reference only. If you need detailed information or engage in related work, please refer to the relevant literature or consult professionals.
Nature:
-Appearance: tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate is a white crystalline solid.
-Solubility: It is poorly soluble in water, but soluble in organic solvents such as ethanol and dichloromethane.
Use:
-Drug research: tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate is commonly used in drug research, especially for the synthesis of biologically active compounds.
-Target compound synthesis: It can also be used to synthesize target compounds with specific functions.
Preparation Method:
The preparation method of tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate can be carried out by the following steps:
1.4-piperazinone reacts with benzylamine to generate 4-(2-benzyl) piperazine -1-one.
2. Reaction of 4-(2-benzyl) piperazin -1-one with tert-butyldimethylsilamide to generate the corresponding silicone.
3. react with tert-butyl formate to generate tert-butyl 4-(2-benzyl) piperazine -1-carboxylate.
4. Finally, tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate is generated by reaction with ammonium butyrate.
Safety Information:
- tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate has limited safety and toxicity information, so it needs to be handled with caution. -Appropriate personal protection measures should be taken during use, such as wearing gloves, goggles and laboratory coatings.
-In case of contact, rinse immediately with plenty of water and seek medical help.
- tert-butyl 4-[(2-aminophenyl)methyl]piperazine-1-carboxylate should be stored in a dry, cool place, away from ignition and strong oxidants.
The above information is for reference only. If you need detailed information or engage in related work, please refer to the relevant literature or consult professionals.
Last Update：2024-04-09 21:00:56
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Product Name: 2-(4-Boc-piperazin-1-yl-methyl)aniline Visit Supplier Webpage Request for quotation
CAS: 885278-02-4
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 885278-02-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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